Southern Indiana Vacation Packages
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Your Southern Indiana Vacation
Make planning your next big adventure a breeze with a Southern Indiana vacation package. Whether it's nature, history or something else that draws you here, our packages will help you discover it all. A trip to Southern Indiana wouldn't be complete without exploring some of its leading cities, starting with Louisville. A couple of the most popular attractions here include KFC Yum Centre and Kentucky Kingdom. Evansville is another favourite with Southern Indiana travellers. Visitors to this destination enjoy Ford Centre and Bally's Evansville Casino. When you're ready to stop daydreaming and start doing, Expedia will help turn your Southern Indiana vacation into a reality.
Top Southern Indiana Vacation Deals
Price found within the past 48 hours. Click for updated prices.
Hyatt Regency Louisville
Downtown Louisville
CA $957
per person
Dec 10 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Louisville (SDF)
8.8/10 Excellent! (1,007 reviews)
Clean rooms, good room service, amazing on site restaraunt and bar. In door pool is kinda small but clean
Reviewed on Sep 23, 2026
Louisville Marriott Downtown
Downtown Louisville
CA $1,060
per person
Dec 10 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Louisville (SDF)
9/10 Wonderful! (1,000 reviews)
The vending machines were completely empty. On every floor. Rooms were clean and beds were comfy. Could use new or different pillows though. They get super flat. Making them get hot fast and obviously uncomfortable. The staff was great and was able to accommodate us checking in pretty late.
Reviewed on Sep 22, 2026
Cottonwood Airport & Expo Hotel Louisville
Shively
CA $959
per person
Dec 10 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Louisville (SDF)
8.6/10 Excellent! (1,004 reviews)
While the hotel was quite nice and the staff was very friendly and helpful, I found the "pet friendly" part of the description misleading. Some hotels state they are "pet ok with fee's" and you expect a fee at every hotel that allows pets, however I was surprised at the amount. I think all hotels that accept pets should be more specific in their information. The fee here was $40, a bit higher than expected. If pet fees were included with the descriptions they could be compared in the same way you include the room rates, helping to make a decision. Otherwise this was a very nice hotel at a reasonable cost.
Reviewed on Sep 23, 2026
The Grady
Downtown Louisville
CA $1,061
per person
Dec 10 - Dec 13
found 1 day ago
Roundtrip non-stop flight included
Calgary (YYC) to Louisville (SDF)
9.4/10 Exceptional! (1,005 reviews)
The bed was incredibly uncomfortable and lumpy. The pillows screwed up my neck. However, Kevin and Farrah at the front desk were incredibly helpful. We ate at the hotel restaurant and the food was good. Overall, the people working there were great! The beds and pillows were not to my liking but that was my only issue.
Reviewed on Sep 23, 2026
Where to stay in Southern Indiana
Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
West Main Historic District
Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.
Downtown Evansville
2 out of top 10 points of interest in this area
Dive into the cultural hub of Evansville, where you can catch a performance by the Evansville Philharmonic Orchestra at Victory Theatre or explore the Children's Museum of Evansville. Don't miss the LST-325 Museum and Ford Center nearby!
Madison Historic District
If you're spending some time in Madison Historic District, Historic District and Lanier Mansion are top sights worth seeing.
Portland
While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.
Downtown French Lick
While Downtown French Lick might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like French Lick Springs Hotel and French Lick Casino.
Ready to book your vacation to Southern Indiana?
Southern Indiana Hotel Deals
Radisson Hotel Louisville North
505 Marriott Drive Clarksville IN
Fully refundable
CA $94
CA $106 total
Oct 25 - Oct 26
includes taxes & fees
Santas Lodge and Resort
91 W CHRISTMAS BLVD Santa Claus IN
Fully refundableReserve now, pay when you stay
CA $147
CA $165 total
Oct 25 - Oct 26
includes taxes & fees
8/10 Very good! (449 reviews)
"Awesome very friendly staff and a amazing staff and the breakfast was awesome Love this place"
Reviewed on Sep 21, 2026
Derby Hotel & Suites
505 K Marriot Dr Clarksville IN
Fully refundableReserve now, pay when you stay
CA $66
CA $75 total
Sep 28 - Sep 29
includes taxes & fees
7/10 Good! (209 reviews)
"Check in was easy and attendant was very friendly and nice to chat with, It’s a good budget hotel if all you need is a place to sleep and get ready for the day. Room was decent and the air conditioner worked very nice, it was nice to have a fridge to store some leftovers."
Reviewed on Sep 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Southern Indiana attractions
KFC Yum Center
8.8/10 (1,621 reviews)
Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.
Photo by Indiana Office of Tourism Development
Holiday World and Splashin' Safari
9.4/10 (294 reviews)
Every day is a holiday at this fun-filled combination theme park and water park, where visitors of all ages can explore roller coasters, raft rides and wave pools.
Whiskey Row
9.2/10 (11 reviews)
Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.
Louisville Slugger Museum
9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
Photo by Nura Mirzaliyeva
Fourth Street Live!
8.4/10 (2,560 reviews)
You can do some window-shopping at Fourth Street Live! during your stay in Louisville. Experience the area's entertainment choices and lively festivals.
Kentucky International Convention Center
8.4/10 (763 reviews)
Learn about the events happening at Kentucky International Convention Center during your trip to Louisville. Amble around the area's riverfront or attend a sporting event.
Ford Center
8.4/10 (472 reviews)
Catch an event at Ford Center during your trip to Evansville. While you're here, you can savor the lively bars.
Louisville Palace
8.2/10 (488 reviews)
You can get tickets for a performance at Louisville Palace on your trip to Louisville. Experience the area's acclaimed theater scene or attend a sporting event.
Frequently asked questions
How much does a Southern Indiana vacation package cost?
We make it simple to travel somewhere new, with Southern Indiana vacation packages starting from just CA $957. You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few activities and tours to your itinerary?
How do I get a cheap travel package to Southern Indiana?
If you love bargains, combine your bookings into a Southern Indiana vacation package. Whether you're looking for flights, hotels, day tours or rental cars, you can book everything in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 airlines and 1,000,000 hotels around the globe to take your pick of. Fly with who you want, stay where you like and save a packet — now that's the ideal getaway!
Where should I stay in Southern Indiana?
Louisville is a fantastic place to explore. It draws in many travelers who come to see its top sights, like Churchill Downs and Muhammad Ali Center.
What are the top hotels in Southern Indiana?
When it comes to properties in Louisville, Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville are two fantastic options. If you're also spending time in Jeffersonville - Clarksville, Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis look forward to welcoming you.
How far in advance should I book my Southern Indiana vacation?
It all depends on the airline, but you can normally browse through international airfares on Expedia up to a year in advance. While it's a good idea to book ahead of time, lucky travelers will sometimes score a cheaper seat only weeks before the date of departure.
What does an Expedia Southern Indiana travel package include?
With Expedia, you can select any combination of flights, car rentals and hotels to create your ideal Southern Indiana travel package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the greater the savings!
What should I know before booking a Southern Indiana travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fabulous discounts. Hotels aren't your only choice, though. Book with us and select from island resorts, rural cottages and everything in between!
Can I choose my airline with a Southern Indiana Expedia vacation package?
Expedia offers access to more than 550 partner airlines globally, so you certainly can. Simply select the carrier that suits you and create the perfect Southern Indiana trip.
If I'm not able to travel, can I cancel my Southern Indiana vacation package?
Yes, you can. We understand that even the best-laid plans can go awry, so we're here to help if you have to make changes to your Southern Indiana vacation package. You may be able to amend or cancel your itinerary at no cost if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
