Southern Indiana Vacation Packages

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Your Southern Indiana Vacation

Make planning your next big adventure a breeze with a Southern Indiana vacation package. Whether it's nature, history or something else that draws you here, our packages will help you discover it all. A trip to Southern Indiana wouldn't be complete without exploring some of its leading cities, starting with Louisville. A couple of the most popular attractions here include KFC Yum Centre and Kentucky Kingdom. Evansville is another favourite with Southern Indiana travellers. Visitors to this destination enjoy Ford Centre and Bally's Evansville Casino. When you're ready to stop daydreaming and start doing, Expedia will help turn your Southern Indiana vacation into a reality.

Top Southern Indiana Vacation Deals

Price found within the past 48 hours. Click for updated prices.
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Downtown Louisville
CA $1,694
per person
Sep 16 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to Louisville (SDF)
8.8/10 Excellent! (1,742 reviews)
Studio 6 Suites Louisville, KY – Airport/Expo Center

Studio 6 Suites Louisville, KY – Airport/Expo Center

Highland Park
CA $2,611
per person
Sep 16 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to Louisville (SDF)
7.4/10 Good! (714 reviews)
Omg id love to just live here my freakinn gosh best place in the entire world

Reviewed on Jul 31, 2026

Cottonwood Airport & Expo Hotel Louisville

Cottonwood Airport & Expo Hotel Louisville

Shively
CA $2,018
per person
Sep 16 - Sep 19
found 1 day ago
Roundtrip non-stop flight included
Edmonton (YEA) to Louisville (SDF)
8.6/10 Excellent! (1,007 reviews)
It was great from the time we checked in to checking out.

Reviewed on Aug 8, 2026

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Downtown Louisville
CA $1,955
per person
Sep 16 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to Louisville (SDF)
9/10 Wonderful! (4,228 reviews)
We loved our stay everyone was so friendly. However did not like the fact housekeeping went in our room after 5 when we did not ask for service and were not present!

Reviewed on Aug 9, 2026

Candlewood Suites Louisville S Fair Expo

Candlewood Suites Louisville S Fair Expo

CA $2,175
per person
Sep 16 - Sep 22
found 1 day ago
Roundtrip non-stop flight included
Vancouver (YVR) to Louisville (SDF)
No reviews

Where to stay in Southern Indiana

Find the best Southern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southern Indiana
The entrance to the Kentucky Science Center with a large circular structure in the foreground.

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

A historic building with a prominent clock tower and dome, surrounded by trees and modern buildings.

Downtown Evansville

2 out of top 10 points of interest in this area

Dive into the cultural hub of Evansville, where you can catch a performance by the Evansville Philharmonic Orchestra at Victory Theatre or explore the Children's Museum of Evansville. Don't miss the LST-325 Museum and Ford Center nearby!

A bridge with a metal truss structure and a highway with vehicles.

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

A weathered tower with a metal sign reading "Better By Far" and a metal structure with the number "3" on top.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

An aerial view of a park with manicured lawns, a central fountain, and a large building with a red dome.

Downtown French Lick

While Downtown French Lick might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like French Lick Springs Hotel and French Lick Casino.

Ready to book your vacation to Southern Indiana?

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Southern Indiana Hotel Deals

Radisson Hotel Louisville North

Radisson Hotel Louisville North

505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
CA $84
CA $95 total
Aug 15 - Aug 16
includes taxes & fees
Radisson Hotel Louisville North
Santas Lodge and Resort

Santas Lodge and Resort

91 W CHRISTMAS BLVD Santa Claus IN
Fully refundableReserve now, pay when you stay
CA $142
CA $159 total
Aug 20 - Aug 21
includes taxes & fees
8/10 Very good! (404 reviews)
"Clean pool areas. Check lamp light bulbs and tv remote batteries."

Reviewed on Aug 8, 2026

Santas Lodge and Resort
Derby Hotel & Suites

Derby Hotel & Suites

505 K Marriot Dr Clarksville IN
Fully refundable
CA $69
CA $78 total
Aug 10 - Aug 11
includes taxes & fees
Derby Hotel & Suites
See all 1,618 properties in Southern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Southern Indiana attractions

A water slide with a yellow and green inflatable raft carrying three people.
Photo by Indiana Office of Tourism Development

Holiday World and Splashin' Safari

9.4/10 (294 reviews)
Every day is a holiday at this fun-filled combination theme park and water park, where visitors of all ages can explore roller coasters, raft rides and wave pools.
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A wall of wooden baseball bats organized by size and weight.

Louisville Slugger Museum

9.2/10 (2,299 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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A river with a bridge, a stadium, and modern buildings.

KFC Yum Center

8.8/10 (1,621 reviews)
Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.
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A bridge with illuminated blue lights at night.
Photo by Melanie Rudolph

Louisville Waterfront Park

8.8/10 (668 reviews)
After visiting Louisville Waterfront Park, make a plan to see the other sights and activities in Louisville. Stroll along the area's riverfront or experience its great live music.
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A wooden barrel room with barrels lined up on both sides and a wooden floor.

Whiskey Row

9.2/10 (11 reviews)
Find out about the history of Louisville when you spend time at Whiskey Row. Attend a sporting event or simply enjoy the lively bars while you're in the area.
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A city street with a large building labeled "FOURTH STREET" and a neon sign for "JIM BEAM."
Photo by Nura Mirzaliyeva

Fourth Street Live!

8.4/10 (2,560 reviews)
You can do some window-shopping at Fourth Street Live! during your stay in Louisville. Experience the area's great live music and entertainment choices.
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Kentucky International Convention Center

8.4/10 (763 reviews)
Learn about the events happening at Kentucky International Convention Center during your trip to Louisville. Amble around the area's riverfront or attend a sporting event.
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Ford Center

8.4/10 (472 reviews)
Catch an event at Ford Center during your trip to Evansville. While you're here, you can savor the lively bars.
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Frequently asked questions

How much does a Southern Indiana vacation package cost?
We make it simple to travel somewhere new, with Southern Indiana vacation packages starting from just CA $1,694. You'll have the flexibility to combine your preferred airlines, hotels and car rental. For the ultimate escape, why not add a few activities and tours to your itinerary?
How do I get a cheap travel package to Southern Indiana?
If you love bargains, combine your bookings into a Southern Indiana vacation package. Whether you're looking for flights, hotels, day tours or rental cars, you can book everything in one place. You'll have plenty of choice at your fingertips too. Expedia has over 550 airlines and 1,000,000 hotels around the globe to take your pick of. Fly with who you want, stay where you like and save a packet — now that's the ideal getaway!
Where should I stay in Southern Indiana?
Louisville is a fantastic place to explore. It draws in many travelers who come to see its top sights, like Churchill Downs and Muhammad Ali Center.
What are the top hotels in Southern Indiana?
When it comes to properties in Louisville, Galt House Hotel Trademark Collection by Wyndham and Radisson Hotel Louisville Jeffersonville are two fantastic options. If you're also spending time in Jeffersonville - Clarksville, Radisson Hotel Louisville Jeffersonville and JW Marriott Indianapolis look forward to welcoming you.
How far in advance should I book my Southern Indiana vacation?
It all depends on the airline, but you can normally browse through international airfares on Expedia up to a year in advance. While it's a good idea to book ahead of time, lucky travelers will sometimes score a cheaper seat only weeks before the date of departure.
What does an Expedia Southern Indiana travel package include?
With Expedia, you can select any combination of flights, car rentals and hotels to create your ideal Southern Indiana travel package. Once you've made your booking, you can add on all the fun stuff like sightseeing tours and activities. Remember — the more you bundle, the greater the savings!
What should I know before booking a Southern Indiana travel package?
You'll save plenty with an Expedia travel package. Combine your airfares, rental cars and hotels and land fabulous discounts. Hotels aren't your only choice, though. Book with us and select from island resorts, rural cottages and everything in between!
Can I choose my airline with a Southern Indiana Expedia vacation package?
Expedia offers access to more than 550 partner airlines globally, so you certainly can. Simply select the carrier that suits you and create the perfect Southern Indiana trip.
If I'm not able to travel, can I cancel my Southern Indiana vacation package?
Yes, you can. We understand that even the best-laid plans can go awry, so we're here to help if you have to make changes to your Southern Indiana vacation package. You may be able to amend or cancel your itinerary at no cost if you've booked in the last 24 hours. Your hotel, airline or car rental company may impose a fee if your booking was made more than 24 hours ago. Have a look at our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.